发明名称 |
MONOCLONAL ANTIBODIES THAT INHIBIT GROWTH OF KAPOSI'S SARCOMA |
摘要 |
The present invention involves the use of monoclonal antibodies specific for Oncostatin M to inhibit the growth potentiating effect of Oncostatin M on Kaposi's Sarcoma associated with AIDS. In particular neutralizing anti-Oncostatin M antibodies inhibit the growth of Kaposi's Sarcoma which is potentiated and maintained by Oncostatin M or a factor found in conditioned media of an HTLV-II transformed T cell line.
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申请公布号 |
CA2039230(C) |
申请公布日期 |
2002.07.30 |
申请号 |
CA19912039230 |
申请日期 |
1991.03.27 |
申请人 |
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发明人 |
SALAHUDDIN, SYED Z.;NAKAMURA, SHUJI;GALLO, ROBERT C.;RADKA, SUSAN F.;LINSLEY, PETER S.;SHOYAB, MOHAMMED |
分类号 |
A61K39/395;A61K35/00;A61K38/00;A61P35/00;C07K16/24;C12P21/08;(IPC1-7):C12P21/08;C12N5/12;G01N33/574 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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