发明名称 |
Methods and kits for improving retroviral-mediated gene transfer utilizing molecules, or mixture thereof, containing retroviral binding domains and target cell binding domains |
摘要 |
The present invention provides a kit to carry out retrovirus-mediated gene transfer into target cells. The kit contains a functional material bearing a retrovirus binding domain, another functional material bearing a target cell binding domain, an artificial substrate for incubating the retrovirus contacted with the target cells, and a target cell growth factor for pre-stimulating target cells to spur them along the cell cycle. The kit of the invention may further comprise a recombinant retroviral vector, necessary buffers, and the like.
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申请公布号 |
US6426042(B1) |
申请公布日期 |
2002.07.30 |
申请号 |
US19990366009 |
申请日期 |
1999.08.02 |
申请人 |
TAKARA SHUZO CO., LTD. |
发明人 |
ASADA KIYOZO;UEMORI TAKASHI;UENO TAKASHI;KOYAMA NOBUTO;HASHINO KIMIKAZU;KATO IKUNOSHIN |
分类号 |
A61K48/00;C07K14/505;C07K14/78;C12N9/10;C12N15/12;C12N15/867;(IPC1-7):G01N31/22 |
主分类号 |
A61K48/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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