| 摘要 |
.beta.,.gamma.-unsaturated .delta.6-lactams, especially 2- azabicyclo[2.2.1]hept-5-en-3-one, are produced by a Diels- Alder reaction of 1,3-dienes with sulfonyl cyanides and subsequent hydrolysis. The sulfonyl cyanides are formed in situ from cyano chloride and the corresponding sulfinates. By the renewed reaction of the sulfinate formed in the hydrolysis of the Diels-Alder adducts with cyanogen chloride, the sulfonyl cyanides are regenerated and a catalytic cyclic process results, 2-Azabicyclo[2.2.1]hept- 5-en-3-one is a starting compound in the synthesis of antiviral nucleoside analogs.
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