PROCESS FOR PREPARING PIROXICAM/CYCLODEXTRIN COMPLEXES, THE PRODUCTS OBTAINED AND THEIR PHARMACEUTICAL COMPOSITIONS

摘要

A process for preparing complexes of piroxicam with cyclodextrins in which the two components in the powder state are premixed and then co- ground in a high energy mill in the presence of steam. The products obtained have technological, physical and biopharmacological characteristics which are advantageous compared with those of liquid-state complexes obtained by traditional methods, and are suitable for preparing pharmaceutical compositions for oral, rectal and topical use.