| 发明名称 |
GLUCKOKINASE ACTIVATORS, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USE |
| 摘要 |
The present invention relates to compounds of formula (I) wherein R<1>, R<2>, R<3> and R<4> are as defined in claim 1 and pharmaceutically acceptable salts thereof. The compounds are glucokinase activators which increase insulin secretion in the treatment of type II diabetes. |
| 申请公布号 |
HU0200396(A2) |
申请公布日期 |
2002.07.29 |
| 申请号 |
HU20020000396 |
申请日期 |
2000.03.20 |
| 申请人 |
F. HOFFMAN-LA ROCHE AG. |
发明人 |
BIZZARRO FRED THOMAS;CORBETT WENDY LEA;FOCELLA ANTONIO;GRIPPO JOSEPH FRANCIS;HAYNES NANCY-ELLEN;HOLLAND GEORGE WILLIAM;KESTER ROBERT FRANCIS;MAHANEY PAIGE E.;SARABU RAMAKANTH |
| 分类号 |
A61K31/17;A61K31/4168;A61K31/42;A61K31/421;A61K31/426;A61K31/433;A61K31/4402;A61K31/455;A61K31/50;A61K31/505;A61P3/10;A61P43/00;C07C275/50;C07C317/44;C07C323/60;C07C323/62;C07D;C07D213/75;C07D213/80;C07D213/803;C07D213/82;C07D233/88;C07D237/20;C07D237/22;C07D239/42;C07D241/28;C07D253/07;C07D261/14;C07D263/34;C07D263/48;C07D277/20;C07D277/38;C07D277/46;C07D277/56;C07D277/58;C07D285/12;C07D285/135 |
主分类号 |
A61K31/17 |
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