发明名称 CHROMENONE AND CHROMANONE DERIVATIVES AS INTEGRIN INHIBITORS, PROCESS FOR PRODUCING THE SAME AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
摘要 The invention relates to compounds having formula (I), wherein R<1>, R<2>, R<3>, R<4>, R<5>, R<7>, R<8>, R<11>, Z, m and n have the meaning cited in claim 1, and to the physiologically acceptable salts and solvates which can be used as integrin inhibitors, especially in the prophylaxis and treatment of circulatory diseases, in case of thrombosis, myocardial infarction, coronary heart diseases, arteriosclerosis, osteoporosis, pathologic processes caused or propagated by angiogenesis and in tumor therapy.
申请公布号 HU0104800(A2) 申请公布日期 2002.07.29
申请号 HU20010004800 申请日期 1999.10.14
申请人 MERCK PATENT GMBH. 发明人 FITTSCHEN CLAUS;GOODMAN SIMON;MAERZ JOACHIM;RADDATZ PETER;WIESNER MATTHIAS
分类号 A61K31/352;A61K31/4178;A61K31/4184;A61K31/4427;A61K31/443;A61P7/02;A61P9/00;A61P9/10;A61P19/00;A61P19/10;A61P21/00;A61P29/00;A61P35/00;A61P43/00;C07D233/66;C07D311/22;C07D311/24;C07D405/12 主分类号 A61K31/352
代理机构 代理人
主权项
地址