| 摘要 |
Co-crystalline mixture of (a) one or more group B components of streptogramins, of general formula: in which A* three eighths * is a radical of general formula: for which R' is H or OH and Y is H, a methylamino radical or a dimethylamino radical, R is an ethyl radical or, when R' is H, R can also represent -CH* superscript dot; dot above *, and R* three eighths * and R* subscript minus * are H, or alternatively A* three eighths * is a radical of formula: R is an isobutyl radical, and R* three eighths * is OH and R* subscript minus * is -CH* superscript dot; dot above *, and (b) one or more group A minority components of streptogramins, of general formula: in which R'' is H or a methyl or ethyl radical. Finely divided physical mixtures and co-precipitates of (a) and (b) are also claimed. A method of purifying the minority components of stretogramins by removal of Group B components from a cocrystallizate is claimed. Two components of Group A where R'' is hydrogen or ethyl are also claimed. |
