Fluid retention assembly for an iontophoretic delivery device and associated method for preparing the same

摘要

A fluid retention assembly for use in association with an iontophoretic drug delivery device comprising: a matrix, wherein the matrix is fabricated from a hydroxylated polyvinyl acetal; a first excipient associated with the matrix, wherein the first excipient comprises a substantially non-ionic thickening agent; and a second excipient associated with the matrix, wherein the second excipient comprises a hydration enhancer. A method for preparing a fluid retention assembly for use in association with an iontophoretic drug delivery device comprising the steps of: providing a first excipient, wherein the first excipient comprises a substantially non-ionic thickening agent; providing a second excipient, wherein the second excipient comprises a hydration enhancer; preparing a solution of the first and second excipients in a solvent; soaking a matrix fabricated from a hydroxylated polyvinyl acetal in the prepared solution; and drying the matrix.