发明名称 |
Ocular iontophoretic device and method for inhibiting vascular endothelial growth factor (VEGF) using the same |
摘要 |
An ocular iontophoretic device for delivering an aptamer to an affected area of a living being's eye for inhibiting VEGF function therein, the device comprising an active electrode assembly associated with a matrix and/or reservoir, wherein the matrix and/or reservoir includes an aptamer capable of inhibiting VEGF function. A method for treating an affected area of a living being's eye, comprising the steps of: associating an aptamer with an ocular iontophoretic device; positioning at least a portion of an ocular iontophoretic device on the eye of the living being; and iontophoretically delivering the aptamer to an affected area of the living being's eye.
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申请公布号 |
US2002099358(A1) |
申请公布日期 |
2002.07.25 |
申请号 |
US20010767032 |
申请日期 |
2001.01.22 |
申请人 |
LLOYD LINDSAY B.;PARKINSON THOMAS M.;SZLEK MALGORZATA |
发明人 |
LLOYD LINDSAY B.;PARKINSON THOMAS M.;SZLEK MALGORZATA |
分类号 |
A61F9/00;A61F9/007;A61N1/30;(IPC1-7):A61M31/00 |
主分类号 |
A61F9/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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