发明名称 PREPARATION OF MICRON-SIZE FELODIPINE PARTICLES BY MICROFLUIDIZATION
摘要 <p>The present invention provides the components for a stable felodipine composition and a process for preparing the composition. The composition includes felodipine, non-covalentaly bound to ß-cyclodextrin, and an optional binder as a moisture carrier component for the migration of hydroxide ions to the non-covalently bound felodipine and ß-cyclodextrin. The felodipine compositon is combined with a carrier comprising cyclodextrin particles, a water-insoluble alkaline component and a swellable polymer.</p>
申请公布号 WO2002056883(A1) 申请公布日期 2002.07.25
申请号 US2001001635 申请日期 2001.01.18
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