发明名称 |
A GENE WHOSE EXPRESSION PROMOTES DIFFERENTIATION OF MYELOID PROGENITOR CELLS INTO NEUTROPHILS AND/OR MONOCYTES/MACROPHAGES |
摘要 |
The present invention provides a human gene sequence that encodes the CDDP-1 polypeptide, which is involved in cell differentiation, in particular differentiation of undifferentiated progenitor cells into neutrophis, monocytes/macrophages, mast cells, and/or erythroid cells. Assays for detecting CDDP-1 expression, vectors that express CDDP-1, methods for using CDDP-1 to include or promote cell differentiation, and transgenic animals deficient in one or both CDDP-1 alleles are described. |
申请公布号 |
WO02057305(A2) |
申请公布日期 |
2002.07.25 |
申请号 |
WO2002US00057 |
申请日期 |
2002.01.04 |
申请人 |
MICHIGAN STATE UNIVERSITY |
发明人 |
SCHWARTZ, RICHARD, C.;TIAN, QIANG |
分类号 |
C07K14/47;C12N5/02;C12N15/12 |
主分类号 |
C07K14/47 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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