| 发明名称 |
STORAGE STABLE TRETINOIN AND 4-HYDROXY ANISOLE CONTAINING TOPICAL COMPOSITION |
| 摘要 |
A long-term storage stable tretinoin and 4-hydroxyanisole composition contains low molecular weight polyethylene glycol, antioxidant, a chelating agent, lower alkanol and water. The chelating agent provides at least two of the functions of oxygen scavaging, free radical chain terminating and reducing. The composition has a pH of 2.5 to 5 and a water content of at least 12%. |
| 申请公布号 |
WO0215851(A3) |
申请公布日期 |
2002.07.25 |
| 申请号 |
WO2001US24287 |
申请日期 |
2001.08.03 |
| 申请人 |
BRISTOL-MYERS SQUIBB COMPANY;PARAB, PRAKASH, V. |
发明人 |
PARAB, PRAKASH, V. |
| 分类号 |
A61K9/08;A61K8/34;A61K8/39;A61K8/67;A61K31/05;A61K31/07;A61K31/203;A61K47/04;A61K47/10;A61K47/12;A61K47/14;A61K47/18;A61K47/20;A61K47/22;A61K47/24;A61K47/26;A61P17/00;A61Q19/00;A61Q90/00 |
主分类号 |
A61K9/08 |
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