NUCLEIC ACID SEQUENCES FROM DROSOPHILA MELANOGASTER THAT ENCODE PROTEINS ESSENTIAL FOR LARVAL VIABILITY AND USES THEREOF

摘要

Nucleotide sequences are isolated from Drosophila melanogaster that code for proteins essential for larval viability. These proteins are useful for discovering newinsecticides based on the essentiality of the nucleotide sequences for Drossophila larval viability. Further provided are recombinant proteins and methods for identifying inhibitors to these proteins. Protein inhibitors active in the methods disclosed herein are useful as insecticidal, ectoparasiticidal, antiparasitic, anthementhic and acaracidal agents.