发明名称 |
SPRAY DRYING PROCESS FOR PREPARING DRY POWDERS |
摘要 |
The present invention provides exemplary systems and methods for producing dry powder formulations. In one embodiment, a system (10) includes at least one conditioning zone (12) having an inlet (20) to introduce an atomized formulation (18) into the conditioning zone. A controller (14, 16) controls temperature and relative humidity of the airflow into the conditioning zone to allow amorphous-to-crystalline transformation of the atomized formulation. In another embodiment, the formulation is suspended in the conditioning zone for a residence time of sufficient duration to allow surface orientation of surface active components. A dryer (24) is coupled to the conditioning zone to dry the atomized formulation, and a collector (28) collects the formulation in powder form.
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申请公布号 |
WO0100312(A9) |
申请公布日期 |
2002.07.25 |
申请号 |
WO2000US18087 |
申请日期 |
2000.06.30 |
申请人 |
INHALE THERAPEUTIC SYSTEMS, INC. |
发明人 |
BENNETT, DAVID, B.;BREWER, THOMAS, K.;PLATZ, ROBERT, M. |
分类号 |
F26B3/06;A61J3/02;A61K9/16;B01D1/18;B01J2/04;F26B21/08;F26B21/10;(IPC1-7):B01J2/04 |
主分类号 |
F26B3/06 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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