发明名称 Use of JAQ1 (monoclonal antibody anti GPVI) as a medicament for the protection against thrombotic diseases
摘要 <p>A medicament for the protection against thrombotic diseases is described that comprises an active principle which induces irreversible inactivation or degradation of the collagen receptor on thrombocytes. Antibodies, especially the humanized monoclonal antibody JAQ1, are the preferred active principle. Further a diagnostic agent for the determination of the expression rate of the collagen receptor GPVI is disclosed which contains the labelled monoclonal or polyclonal antibody directed against the GPVI epitope, preferably as defined by JAQ1. <IMAGE></p>
申请公布号 EP1224942(A1) 申请公布日期 2002.07.24
申请号 EP20010101406 申请日期 2001.01.23
申请人 NIESWANDT, BERNHARD, DR. 发明人 NIESWANDT, BERNHARD, DR.
分类号 G01N33/50;A61K39/395;A61K45/00;A61P7/02;A61P9/10;C07K16/28;C12N5/10;C12N15/02;C12P21/08;G01N33/53;G01N33/566;G01N33/577;(IPC1-7):A61K39/395;C12N5/20 主分类号 G01N33/50
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