| 摘要 |
<p>Peptides of the formula (I) R-X-ProIleGlu-W-Y-Z (wherein R is hydrogen, an amino-protective group, residue carrying one or two D- or L-amino acid, X is Lys or Arg, W is Phe or Phe(NO2) (in which Phe(NO2) is p-nitrophenylalanine.), Y is Phe, Phe(NO2), Tyr, 3,5-diiodotyrosine, norleucine, Leu, Asp(OBzl) or Met (in which OBzl is benzyloxy.), Z is an aniline, aminocoumarin or aminonaphthalene derivative residue.), or acid addition salts thereof. Peptides of the formula (I) are specific substrates for human pepsin I, so they are used in assaying human pepsin I or human pepsinogen I. These peptide are useful in the diagnosis of gastric diseases such as gastric cancer and gastric ulcer.</p> |
