发明名称 |
WD-40 derived peptides and uses thereof |
摘要 |
The present invention relates to a polypeptide composition effective to alter the activity of a first protein that interacts with a second protein, where the second protein contains at least one WD-40 region. The polypeptides of the present invention typically have between 4 and 50 amino acids whose sequence is the same as a sequence of the same length in the WD-40 region of the second protein. The invention further includes a method of altering the activity of the above described first protein. In one embodiment of the invention the polypeptide composition is effective to alter the activity of a protein kinase C, where the protein kinase C interacts with a second protein, and the second protein contains at least one WD-40 region (e.g., RACK1).
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申请公布号 |
US6423684(B1) |
申请公布日期 |
2002.07.23 |
申请号 |
US19950487072 |
申请日期 |
1995.06.07 |
申请人 |
THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY |
发明人 |
MOCHLY-ROSEN DARIA;RON DORIT |
分类号 |
C07K5/117;C07K14/00;C07K14/47;C07K14/705;(IPC1-7):A61K38/16;A61K38/00 |
主分类号 |
C07K5/117 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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