| 发明名称 |
Substituted pyrazoles as p38 kinase inhibitors |
| 摘要 |
A class of pyrazole derivatives is described for use in treating p38 kinase mediated disorders. Compounds of particular interest are defined by Formula IAwherein R1, R2, R3 and R4 are as described in the specification.
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| 申请公布号 |
US6423713(B1) |
申请公布日期 |
2002.07.23 |
| 申请号 |
US20010918481 |
申请日期 |
2001.07.31 |
| 申请人 |
G. D. SEARLE & COMPANY |
发明人 |
ANANTANARAYAN ASHOK;CLARE MICHAEL;COLLINS PAUL W.;CRICH JOYCE ZUOWU;DEVRAJ RAJESH;FLYNN DANIEL L.;GENG LIFENG;GRANETO MATTHEW J.;HANAU CATHLEEN E.;HANSON GUNNAR J.;HARTMANN SUSAN J.;HEPPERLE MICHAEL;HUANG HE;KOSZYK FRANCIS J.;LIAO SHUYUAN;METZ SUZANNE;PARTIS RICHARD A.;PERRY THAO D.;RAO SHASHIDHAR N.;SELNESS SHAUN RAJ;SOUTH MICHAEL S.;STEALEY MICHAEL A.;TALLEY JOHN JEFFREY;VAZQUEZ MICHAEL L.;WEIER RICHARD M.;XI XIANGDONG;KHANNA ISH K.;YU YI |
| 分类号 |
A61K31/415;A61K31/44;A61K31/4439;A61K31/445;A61K31/454;A61K31/47;A61K31/496;A61K31/50;A61K31/505;A61K31/506;A61K31/52;A61K31/5377;A61P1/04;A61P9/00;A61P11/00;A61P11/06;A61P13/12;A61P19/00;A61P19/02;A61P19/06;A61P29/00;A61P29/02;A61P43/00;C07D401/04;C07D401/14;C07D403/04;C07D403/14;C07D405/14;C07D409/14;C07D413/14;C07D417/14;C07D453/02;C07D471/04;C07D473/00;C07D487/04;(IPC1-7):A61K31/496;A61K31/452;C07D413/02 |
主分类号 |
A61K31/415 |
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