发明名称 Imidazole derivative functioning as phosphodiesterase VII inhibitor, its use, and pharmaceutical preparation in which the derivative is comprised
摘要 <p>The invention relates to imidazole derivatives of formula (I), wherein R<1> means H, A, benzyl, indane-5-yl, 1,2,3,4-tetrahydro-naphthaline-5-yl, dibenzothiophene-2-yl or phenyl that is unsubstituted or substituted once, twice or three times by means of Hal, A, A-CO-NH, benzyloxy, alkoxy, COOH or COOA, R<2> means H or A, X means O or S, Hal means F, Cl, Br or I and A means alkyl with 1 to 6 C-atoms. The invention also relates to the physiologically acceptable salts and/or solvates thereof acting as phosphodiesterase VII inhibitors. The invention further relates to the use thereof for producing a medicament.</p>
申请公布号 CZ20021251(A3) 申请公布日期 2002.07.17
申请号 CZ20020001251 申请日期 2000.10.10
申请人 MERCK PATENT GMBH 发明人 EGGENWEILER MICHAEL;ROCHUS JONAS;WOLF MICHAEL;GASSEN MICHAEL;POSCHKE OLIVER
分类号 A61K31/4188;A61P1/04;A61P3/10;A61P7/00;A61P9/10;A61P11/00;A61P11/06;A61P17/00;A61P17/06;A61P19/02;A61P19/10;A61P25/00;A61P25/28;A61P29/00;A61P31/04;A61P35/00;A61P37/00;A61P37/04;A61P37/06;A61P43/00;C07D491/04;C07D491/052;C07D495/04;(IPC1-7):C07D495/04;A61K31/418 主分类号 A61K31/4188
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