Production of pyrogen controlled water

摘要

A unit (1) for producing pyrogen controlled water on a small to medium factory scale comprises a number of charged ultrafiltration units (10) arranged in parallel. Orifice plates (15) are used to restrict and control the flow of deionised water to each filter (10). The filter units (10) are mounted on a frame (2) with a wheeled chassis (3) which may be pushed or moved by a forklift truck to a site where pyrogen controlled water is required. The unit (1) has an inlet line (4) for connection to a supply of deionised water and an outlet line (6) for connection to a user of pyrogen controlled water. The unit (1) may be purged with nitrogen from a supply (18). Sampling ports (17) in a common supply inlet (4) and a common outlet (6) ensure that the filtration efficiency can be closely monitored. The flow of water is monitored by a flowmeter (19) and pressure sensors (16) upstream of each filter facilitate a high level of control.