发明名称 |
1-(4-arylpiperazin-1-yl)-omega-[N-(alphaomega-dicarboximido)]-alkanes useful as uro-selective alpha1-adrenoceptor blockers |
摘要 |
Novel piperzine derivatives substituted on one nitrogen by an aromatic system and on the other nitrogen by (2,5-dioxopyrrolidin)-1-yl) alkanes or (2,6-dioxopiperidin-1-yl) alkanes have been found to exhibit selective alpha1A adrenergic activity. The compounds are useful for treatment of disease conditions, such as peripheral vascular disease, congestive heart failure, hypertension and especially benign prostatic hypertrophy.
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申请公布号 |
US6420366(B1) |
申请公布日期 |
2002.07.16 |
申请号 |
US20000577788 |
申请日期 |
2000.05.24 |
申请人 |
RANBAXY LABORATORIES LIMITED |
发明人 |
ANAND NITYA;SINHA NEELIMA;JAIN SANJAY;MEHTA ANITA;GUPTA JANG BAHADUR |
分类号 |
A61K31/496;C07D207/40;C07D207/404;C07D207/408;C07D211/88;C07D401/06;(IPC1-7):A61K31/495 |
主分类号 |
A61K31/496 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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