发明名称 Sulphur derivatives with a retroamide bond as endothelin-converting enzyme inhibitors
摘要 Products of formula (1), wherein R1 is particularly phonyl or biphenyl optionally substituted by halogen n1 and n2 are 0 or 1, R2 is particularly hydrogen or methyl substituted by phenyl, which may in turn be substituted, and A is partcularly carboxy or alkyl substituted particularly by phenoxy, as well as all isomers and organic and inorganic base addition salts therof, are disclosed.
申请公布号 US6420341(B1) 申请公布日期 2002.07.16
申请号 US19980142288 申请日期 1998.10.30
申请人 AVENTIS PHARMA S.A. 发明人 DEPREZ PIERRE;DUMAS JACQUES;GUILLAUME JACQUES
分类号 A61K31/00;A61K31/165;A61K31/195;A61K31/275;A61K31/38;A61K31/381;A61K31/40;A61K31/403;A61K31/404;A61K31/405;A61P9/00;A61P13/00;A61P13/12;A61P43/00;C07C323/29;C07C323/41;C07D209/20;C07D209/40;C07D257/04;C07D333/24;(IPC1-7):A61K38/00 主分类号 A61K31/00
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