发明名称 Intermediate for synthesis of anticoagulant agents
摘要 This invention relates to a chemical intermediate wherein f is 0, 1, 2 or 3, which is useful for the synthesis of a compound of the Formula I X-C(O)-Y-G-RI (wherein X, Y, G and R have the values defined in the description), or a pharmaceutically acceptable salt thereof, which compound of Formula I or salt and pharmaceutical compositions comprising such a compound or salt are useful as thrombin inhibitors, coagulation inhibitors and agents for the treatment of thromboembolic disorders.
申请公布号 US6008367(A) 申请公布日期 1999.12.28
申请号 US19990237012 申请日期 1999.01.25
申请人 ELI LILLY AND COMPANY 发明人 KLIMKOWSKI, VALENTINE JOSEPH;SCHACHT, AARON LEIGH;WILEY, MICHAEL ROBERT
分类号 A61K38/00;A61K31/165;A61P7/02;C07C311/06;C07D205/04;C07D207/16;C07D209/42;C07D217/26;C07D401/06;C07K5/02;C07K5/06;C07K5/062;C07K5/065;C07K5/078;(IPC1-7):C07D261/20 主分类号 A61K38/00
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