FLAVANONE DERIVATIVES AND COMPOSITION FOR PREVENTING OR TREATING BLOOD LIPID LEVEL-RELATED DISEASES COMPRISING SAME

摘要

PURPOSE: Provided are flavanone derivatives which decrease blood lipid level, inhibits cholesterol metabolism related enzyme, treat and prevent arteriosclerosis, and protect liver function. Also, provided are a composition for preventing or treating blood lipid level-related diseases comprising same. CONSTITUTION: The flavanone derivative having excellent improving effects on lipid metabolism is represented by the formula(1), wherein R1 is R5 or R6CO-; R2 is H or R6CO-; R3 is H, CH3, R5 or R6CO-; R4 is H, OH, OR5 or R6COO-; R5 is unsubstituted or substituted C2-C5 alkyl with phenyl which is substituted with at least one of C1-C3 alkyl, OH, Cl or NO2, unsubstituted or substituted C1-C5 alkyl with substituted naphthyl which is substituted with at least one of C1-C3 alkyl, OH, Cl or NO2, or C10-18 alkyl or alkenyl; and R6 is C10-18 alkenyl or unsubstituted or substituted aryl with at least one of C1-3 alkyl, OH or NO2.