发明名称 |
St - B17 serotonin receptor |
摘要 |
Genes encoding the St-B17 serotonin receptor protein were cloned and characterized from a rat striatum mRNA and a human genomic library. The St-B17 receptor has nucleotide and amino acid homology with previously described 5-HT genes and can bind ligands that are known to interact with serotonin receptors. In addition, the levels of intracellular cAMP in cells transfected with the receptor gene respond in a dose dependent manner to introduction of serotonin in the media.
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申请公布号 |
US2002091235(A1) |
申请公布日期 |
2002.07.11 |
申请号 |
US20010829631 |
申请日期 |
2001.04.10 |
申请人 |
SIBLEY DAVID R.;MONSMA FREDERICK J.;HAMBLIN MARK |
发明人 |
SIBLEY DAVID R.;MONSMA FREDERICK J.;HAMBLIN MARK |
分类号 |
A61K38/00;C07K14/705;C12N15/12;C12P21/08;(IPC1-7):C07K1/00 |
主分类号 |
A61K38/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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