PARAMAGNETIC METAL-PHTHALOCYANINE COMPLEX COMPOUNDS AND CONTRAST AGENT USING THE SAME

摘要

The present invention refers to the novel paramagnetic metal-phthalocyanine complexes and pharmaceutically acceptable salts thereof which are useful as contrast agents for MRI (Magnetic Resonance Imaging), diagnostic X-ray imaging and computed tomography(CT) .The present invention also refers to contrast agents for imaging comprising the new paramagnetic metal-phthalocyanine complexes described above. The new contrast agents of the present inventions show high imaging enhancement effects at lower concentrations and are more safe over the previously reported contrast agents.