发明名称 |
NEW ARYLPIPERAZINYLALKYL-3 (2H)-PYRIDAZINONES |
摘要 |
A description is given of new arylpiperazinylalkyl-3(2H)-pyridazinones of general formula(I) and their preparation and their addition salts with pharmaceutically acceptable acids,(see formula I) in which R1 is a methyl or phenyl radical, R2 is a hydrogen atom or a methyl radical, n takes values between 2 and 4, and R3 is a naphthyl radical or a phenyl radical, which are substituted by a radical such as methoxyl, trifluoromethyl and chlorine. The compounds present affinity for serotonin 5HT 1A and 5HT2 receptors and for dopamine D2 receptors, and can be useful as antipsychotics.
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申请公布号 |
CA2310873(A1) |
申请公布日期 |
2000.12.04 |
申请号 |
CA20002310873 |
申请日期 |
2000.06.02 |
申请人 |
FAES, FABRICA ESPANOLA DE PRODUCTOS QUIMICOS Y FARMACEUTICOS, S.A. |
发明人 |
ORJALES VENERO, AURELIO;GARCIA-DOMINGUEZ, NEFTALI |
分类号 |
C07D401/06;A61K31/501;A61P25/18;A61P43/00;C07D237/14;(IPC1-7):C07D237/14 |
主分类号 |
C07D401/06 |
代理机构 |
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地址 |
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