发明名称 |
PHARMACEUTICAL COMPOSITIONS OF A NON-ENTERIC COATED PROTON PUMP INHIBITOR WITH A CARBONATE SALT AND BICARBONATE SALT COMBINATION |
摘要 |
A method for treating gastric acid disorders with a non-enteric coated proton pump inhibitor in a pharmaceutically acceptable carrier including a bicarbonate salt of a Group IA metal and a carbonate salt of a Group IA metal; and a pharmaceutical composition of a non-enteric coated proton pump inhibitor in a pharmaceutically acceptable carrier including a bicarbonate salt of a Group IA metal and a carbonate salt of a Group IA metal are disclosed. A presently preferred proton pump inhibitor is lansoprazole, a presently preferred bicarbonate salt is sodium bicarbonate, and a presently preferred carbonate salt is sodium carbonate. The composition is a fast-acting formulation which reduces the undesirable belching associated with proton pump inhibitor formulations that contain high doses of sodium bicarbonate. |
申请公布号 |
WO02053097(A2) |
申请公布日期 |
2002.07.11 |
申请号 |
WO2001US48320 |
申请日期 |
2001.12.12 |
申请人 |
TAP PHARMACEUTICAL PRODUCTS INC. |
发明人 |
TANEJA, RAJNEESH;GUPTA, PRAMOD |
分类号 |
C07D401/12;A61K9/00;A61K9/16;A61K31/4439;A61K45/00;A61K47/02;A61P1/04;A61P43/00 |
主分类号 |
C07D401/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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