摘要 |
A methods of treating an infection comprises administering a therapeutically effective amount of a compound described by Formula (I), wherein: X may be O, S, or NR' wherein R' is H or loweralkyl; R1 and R2 may be independently selected from the group consisting of H, loweralkyl, oxyalkyl, alkoxyalkyl, cycloalkyl, aryl, hydroxyalkyl, aminoalkyl, and alkylaminoalkyl; R3 and R4 are each independently selected from the group consisting of H, loweralkyl, halogen, oxyalkyl, oxyaryl, and oxyarylalkyl; R5 is represented by a formula selected from the group consisting of: (a) and (b), wherein: X1, X2, and X3 are independently selected from O and S; and R6 and R7 are independently selected from the group consisting of loweralkyl, aryl, alkylaryl, oxyaryl, an ester-containing substituent, and oxyalkyl; or a pharmaceutically acceptable salt thereof. |
申请人 |
THE UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL;BOYKIN, DAVID, W.;RAHMATHULLAH, M., SYED;TIDWELL, RICHARD, R.;HALL, JAMES, E. |
发明人 |
BOYKIN, DAVID, W.;RAHMATHULLAH, M., SYED;TIDWELL, RICHARD, R.;HALL, JAMES, E. |