FACILITATIVE TRANSPORTER (FT1 AND FT2) FROM DROSOPHILA MELANOGASTER AND USES THEREOF

摘要

Facilitative Transporter (FT) nucleic acids and proteins that have been isolated from Drosophila melanogaster , referred to as FT1 and FT2, are described. The FT nucleic acids and proteins can be used to genetically modify metazoan invertebrate organisms, such as insects and worms, or cultured cells, resulting in FT expression or mis-expression. The genetically modified organisms or cells can be used in screening assays to identify candidate compounds that are potential pesticidal agents or therapeutics that interact FT protein. They can also be used in methods for studying FT activity and identifying other genes that modulate the function of, or interact with, the FT gene.