摘要 |
<p>There are provided new kojic acid derivatives represented by the following formula 1 and a preparation method thereof: (I) (wherein, R is an alkyl group having 2-10 of carbon number substituted by a lower alkyl group having 1-6 of carbon number or not substituted; an alkenyl group having 2-10 of carbon number; a benzyl group substituted or not substituted; or a pyridine group substituted or not substituted). The kojic acid derivative of the formula (1) exhibits a strong activity of inhibiting melanin formation and curing pigmentation of the skin, to be incorporated into cosmetics for whitening effect.</p> |