摘要 |
PROBLEM TO BE SOLVED: To provide a production method of 6-aminomethyl-6,11-dihydro-5H- dibenz[b,e]azepine which is industrially useful. SOLUTION: The production method of 6-aminomethyl-6,11-dihydro-5H- dibenz[b,e]azepine represented by formula (III) is characteristically made through N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6-yl)methyl]-o-hydroxybenzamido represented by formula (II) which is formed by reducing 6-phthalimidomethyl-5H- dibenz[b,e]azepine represented by formula (I) with a metal hydride compound or a metal hydride complex compound. N-[(6,11-dihydro-5H-dibenz[b,e]azepin-6- yl)methyl]-o-hydroxybenzamido represented by formula (II) is useful for the production.
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