DERMATO-SURGICAL METHOD FOR TREATING HYPOTROPHIC CICATRICES

摘要

medicine. SUBSTANCE: method involves preliminarily taking biopsy samples as a piece of healthy skin epidermis to select a culture of living keratinocytes. Then, cosmetic hypotrophic cicatrix filing operation is carried out to basal epidermis layer and the preliminarily cooled dermal equivalent produced as a mixture of fibroblasts with collagen and growth medium taken in non-polymerized form to fill micro-relief of the filed hypotrophic cicatrix surface. After having polymerized the dermal equivalent, keratinocyte culture is arranged over the polymerized dermal equivalent surface. The keratinocyte culture is administered in particular cases as suspension. The keratinocyte culture is administered in particular cases as multilayer flat plates with no substrate. The keratinocyte culture is administered in particular cases as multilayer flat plates with substrate. EFFECT: enhanced effectiveness in removing and healing skin defects. 4 cl