发明名称 ENZYMATIC COMPOSITION FOR CLINICAL EXAMINATION
摘要 <p>Disclosed is a stabilized enzyme composition for use in clinical examination, comprising: (a) an enzyme component comprising at least two enzymes selected from the group consisting of alkaline phosphatase, creatine kinase and alanine aminotransferase; (b) a stabilizer component comprising effective stabilizing amounts of an albumin, and at least one saccharide selected from the group consisting of trehalose and sorbitol; and (c) an aqueous medium having dissolved therein the components (a) and (b). The enzyme composition of the present invention is stable for a prolonged period of time not only under non-freeze refrigeration conditions, but also under freezing conditions or under conditions for non-freeze refrigeration after thawing of the frozen composition, as compared to the conventional enzymatic compositions. The enzyme composition of the present invention can be advantageously used for the purpose of checking the precision in measurement, correcting measured values and calibrating the amount and activity of an enzyme, in a clinical examination for measuring the enzymatic activity in a sample, such as serum or the like.</p>
申请公布号 EP0791658(B1) 申请公布日期 2002.07.10
申请号 EP19950936772 申请日期 1995.11.10
申请人 ASAHI KASEI KABUSHIKI KAISHA 发明人 AOKI, RYOJI;UEDA, SHIGERU
分类号 C12Q1/32;C12Q1/42;C12Q1/48;C12Q1/50;C12Q1/52;G01N33/50;G01N33/96;(IPC1-7):C12Q1/42 主分类号 C12Q1/32
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