发明名称 |
Malaria merozoite antigen subunit vaccine |
摘要 |
An immunogenic polypeptide for use in inducing an immune response against Plasmodium infection comprises an amino acid sequence corresponding to a non-full length fragment of the apical membrane antigen 1 (AMA-1) of Plasmodium species which does not include a transmembrane domain thereof, and which is stabilised by folding thereof. Production of the immunogenic polypeptide by expression of a recombinant DNA molecule in a host cell, and methods and compositions using the immunogenic polypeptide are disclosed.
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申请公布号 |
US6417341(B1) |
申请公布日期 |
2002.07.09 |
申请号 |
US19960687387 |
申请日期 |
1996.10.07 |
申请人 |
SARAMANE PTY., LTD. |
发明人 |
ANDERS ROBIN FREDRIC;CREWTHER PAULINE ELIZABETH;LEET MARY SHU MAI;HODDER ANTHONY NEIL;PYE DAVID |
分类号 |
A61K39/00;C07K14/445;(IPC1-7):C07H21/04;C07K14/00;C12N15/00 |
主分类号 |
A61K39/00 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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