发明名称 |
PROLONGED RELEASE PREPARATION AND POLYMERS THEREOF |
摘要 |
PROLONGED RELEASE PREPARATION AND POLYMERS THEREOF 1. A polymer for a prolonged release preparation which comprises (A) a polylactic acid and (B) a copolymer of glycolic acid and a hydroxycarboxylic acid of general formula wherein R stands for an alkyl group having 2 to 8 carbons, at a weight ratio of (A) and (B) in the range of 10/90 to 90/10. The drug is released at a constant rate from the preparation over the total release period without a large burst at the initial stage. Furthermore, the drug release period of the preparation can be freely controlled by varying the blending ratio of (A) and (B). |
申请公布号 |
CA2053468(C) |
申请公布日期 |
2002.07.09 |
申请号 |
CA19912053468 |
申请日期 |
1991.10.15 |
申请人 |
TAKEDA CHEMICAL INDUSTRIES, LTD. |
发明人 |
YAMADA, MINORU;ISHIGURO, SEIKO;OGAWA, YASUAKI |
分类号 |
A61K9/14;A61K9/16;A61K9/22;A61K9/50;A61K9/52;A61K38/00;A61K45/00;A61K47/34;C08G63/08;C08L67/00;C08L67/04 |
主分类号 |
A61K9/14 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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