MICROORGANISM CORYNEBACTERIUM AMMONIAGENES CJIP009 BEING CAPABLE OF PRODUCING 5'-INOSINIC ACID IN HIGHER YIELD AND A PRODUCING METHOD OF 5'-INOSINIC ACID BY USING THE SAME

摘要

PURPOSE: Provided is a microorganism Corynebacterium ammoniagenes CJIP009 being capable of producing 5'-inosinic acid in higher yield and concentration band a producing method of 5'-inosinic acid economically by direct fermentation using the same. CONSTITUTION: Corynebacterium ammoniagenes CJIP009(KCCM-10226) produces and accumulates 5'-inosinic acid in high concentration and yield, and has resistance to L-glutamine analogue including Azaserine and DON(6-diazo-5-oxo-L-norleucine), and L-proline analogue including 3,4-dehydroproline, L-azetidine-2-carboxylic acid, L-thiazolidine-4-carboxylic acid, (S)-2,2-dimethyl-4-oxazoliden carboxylic acid, (S)-5,5-dimethyl-4-thiazolide carboxylic acid, (4S, 2RS)-2-ethyl-4-thiazolidine-carboxylic acid, (2S, 4S)-4-hydroxy-2-pyrroline-carboxylic acid, 2-piperidinecarboxylic acid, and 2,5-pyrrolidinedione.