发明名称 |
METHODS |
摘要 |
A method of enhancing antigen presentation, comprising the step of supplying to an antigen presenting cell such as a dendritic cell, or precursor cell, a modulator, preferably an inhibitor, fo Toll-related receptor (TRR) signalling. A method of inhibiting antigen presentation, comprising the step of supplying to an antigen presenting cell such as a dentritic cell, or precursor cell, a modulator, preferably an enhancer of Toll-related receptor (TRR) signalling. The inhibitor or TRR signalling may be a dominant negative mutant of MyD88, for example MyD881pr. |
申请公布号 |
WO02051430(A2) |
申请公布日期 |
2002.07.04 |
申请号 |
WO2001GB05724 |
申请日期 |
2001.12.21 |
申请人 |
SYNOVIS LIMITED;FOXWELL, BRIAN, MAURICE, JOHN;FELDMANN, MARC |
发明人 |
FOXWELL, BRIAN, MAURICE, JOHN;FELDMANN, MARC |
分类号 |
G01N33/50;A61K38/17;A61K39/00;A61K39/39;A61K45/00;A61K48/00;A61P31/12;A61P35/00;A61P37/02;C12N5/0784;C12N15/09;C12Q1/68;G01N33/15 |
主分类号 |
G01N33/50 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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