TRANSFECTION COMPLEXES (TRANSOPLEX) HAVING A REDUCED TOXICITY, A HIGHER PHYSICAL STABILITY, AND A HIGHER TRANSFECTION EFFICIENCY, AND A METHOD FOR THE PRODUCTION THEREOF
摘要
The invention relates to complexes for use in transfection that comprise material to be transfected and lipid particles, which consist of lipids that are solid at room temperature or of lipid mixtures, which contain lipids that are solid at room temperature and lipids that are semi-solid or liquid at room temperature, whereby the lipid particles have modifying agents on their surface.
申请公布号
WO02051446(A2)
申请公布日期
2002.07.04
申请号
WO2001EP15287
申请日期
2001.12.21
申请人
PHARMASOL GMBH;KNEUER, CARSTEN;LEHR, CLAUS-MICHAEL;OLBRICH, CARSTEN;MUELLER, RAINER, HELMUT
发明人
KNEUER, CARSTEN;LEHR, CLAUS-MICHAEL;OLBRICH, CARSTEN;MUELLER, RAINER, HELMUT