Process for the preparation of N-(substituted phenyl)-3-alkyl-,aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl-and haloalkylpropanamide compounds

摘要

The present invention provides an improved process for the preparation of N-(substituted phenyl)-3-alkyl-, aryl- and heteroarylsulfonyl-2-hydroxy-2-alkyl- and haloalkylpropanamide compounds of formula I The formula I compounds exhibit antiandrogenic activity and are useful in the treatment of malignant or benign pro static disease or of androgen dependent disease conditions such as acne, hirsutism or seborrhoea.