发明名称 PROCESS FOR THE PREPARATION OF .ALPHA.-AMINOSUBSTITUTED CARBOXYLIC ACID AMIDES
摘要 The invention relates to a process for the preparation of .alpha.- aminosubstituted carboxylic acid amide compounds and/or their salts comprisi ng reacting a carboxylic acid amine of a primary amine with a nitrosylating age nt in the presence of a base followed by hydrolysis to give a hydroxy imino derivative followed by hydrogenation and if necessary converting a base or acid of the .alpha.-aminosubstituted carboxylic acid amine into one of its salts.
申请公布号 CA2433089(A1) 申请公布日期 2002.07.04
申请号 CA20012433089 申请日期 2001.12.11
申请人 MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG 发明人 HARTIG, THORSTEN;ENKE, STEFFEN
分类号 C07D209/40;C07D223/16;(IPC1-7):C07D223/16 主分类号 C07D209/40
代理机构 代理人
主权项
地址