发明名称 |
PROCESS FOR THE PREPARATION OF .ALPHA.-AMINOSUBSTITUTED CARBOXYLIC ACID AMIDES |
摘要 |
The invention relates to a process for the preparation of .alpha.- aminosubstituted carboxylic acid amide compounds and/or their salts comprisi ng reacting a carboxylic acid amine of a primary amine with a nitrosylating age nt in the presence of a base followed by hydrolysis to give a hydroxy imino derivative followed by hydrogenation and if necessary converting a base or acid of the .alpha.-aminosubstituted carboxylic acid amine into one of its salts.
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申请公布号 |
CA2433089(A1) |
申请公布日期 |
2002.07.04 |
申请号 |
CA20012433089 |
申请日期 |
2001.12.11 |
申请人 |
MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG |
发明人 |
HARTIG, THORSTEN;ENKE, STEFFEN |
分类号 |
C07D209/40;C07D223/16;(IPC1-7):C07D223/16 |
主分类号 |
C07D209/40 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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