发明名称 ANILINE DERIVATIVES OR SALTS THEREOF AND CYTOKINE PRODUCTIONINHIBITORS CONTAINING THE SAME
摘要 Cytokine production inhibitors containing as the active ingredient aniline derivatives represented by the general formula (I) or salts thereof: (I) wherein A is CO or SO~2; Cy is aryl or a heterocyclic group; R1~ and R2~ are each independently halogeno, cyano, nitro, optionally substituted alkyl, optionally substituted alkenyl, optionally substituted alkynyl, optionally substituted cycloalkyl, optionally substituted cycloalkenyl, optionally substituted aryl, an optionally substituted heterocyclic group, optionally substituted amino, or B-Q; R3~ is M1~-M2~-R5~; R4~ is hydrogen or optionally substituted alkyl; x is an integer of 0 to 5; y is an integer of 0 to 4; and z is an integer of 0 to 1.
申请公布号 CA2432713(A1) 申请公布日期 2002.07.04
申请号 CA20012432713 申请日期 2001.12.21
申请人 ISHIHARA SANGYO KAISHA, LTD. 发明人 OKADA, TAKASHI;KATO, FUMINORI;YUKI, SHUNJI;KIMURA, HIROHIKO;YAMAMOTO, KAZUHIRO
分类号 A61K31/04;A61K31/15;A61K31/167;A61K31/18;A61K31/428;A61K31/44;A61K31/4439;A61K31/444;A61K31/4545;A61K31/496;A61K31/505;A61K31/5375;A61P3/10;A61P11/06;A61P17/04;A61P19/02;A61P21/04;A61P27/02;A61P27/14;A61P27/16;A61P29/00;A61P37/06;A61P37/08;A61P43/00;C07C233/65;C07C233/66;C07C233/75;C07C233/76;C07C233/80;C07C235/56;C07C235/64;C07C245/08;C07C255/57;C07C311/21;C07C311/46;C07C311/51;C07C323/42;C07D213/40;C07D213/61;C07D213/64;C07D213/643;C07D213/70;C07D213/71;C07D213/74;C07D213/75;C07D213/76;C07D239/46;C07D239/47;C07D241/44;C07D277/46;C07D277/52;C07D277/62;C07D277/66;C07D277/82;C07D295/135;C07D401/12;(IPC1-7):A61K31/167;C07D295/12;C07C317/44;A61K31/440;A61K31/443;A61K31/454;A61K31/498;A61K31/537;C07C323/62;C07D239/69 主分类号 A61K31/04
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