| 发明名称 |
Novel antiangiogenic peptides |
| 摘要 |
The present invention provides an antiangiogenic polypeptide having the amino acid sequence set forth in SEQ ID NO: 1 or a portion thereof which is effective to inhibit endothelial cell proliferation as determined by the capillary EC proliferation assay. Preferably, the portion has at least 50% inhibition of bFGF-stimulated EC proliferation at 5 Tg/ml, more preferably 75% inhibition, most preferably 95% inhibition.
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| 申请公布号 |
US2002086420(A1) |
申请公布日期 |
2002.07.04 |
| 申请号 |
US20010954968 |
申请日期 |
2001.09.18 |
| 申请人 |
CHILDREN'S MEDICAL CENTER CORPORATION |
发明人 |
MOSES MARSHA;WU INMIN;FERNANDEZ CECILIA |
| 分类号 |
C12N15/09;A61K31/711;A61K38/00;A61K48/00;A61P15/02;A61P17/02;A61P17/06;A61P19/02;A61P27/02;A61P27/06;A61P29/00;A61P35/00;A61P35/02;A61P35/04;A61P43/00;C07K14/47;C07K14/81;C12N1/15;C12N1/19;C12N1/21;C12N5/10;(IPC1-7):A61K48/00;A61K38/48;C12N9/64;C12Q1/70;A61K31/70;A01N43/04;C12P19/34;A61K39/12;C07K2/00;C07K4/00;C07K5/00;C07K7/00;C07K14/00;C07K16/00;C07K17/00;C12N15/00;C12N15/63;C12N15/70;C12N15/74 |
主分类号 |
C12N15/09 |
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