| 发明名称 |
MODULATORS OF THE INTERACTION BETWEEN ARP2/3 AND CORTACTIN OR HS-1 |
| 摘要 |
<p>The invention relates to methods for screening compounds for their ability to modulate actin polymerization. The invention is also related to compounds which modulate actin polymerization. More specifically, the invention is related to methods of screening compounds which modulate the interaction of cortactin or HS-1 with Arp2/3. The invention is also related to compounds which modulate the interaction of cortactin or HS1 with Arp2/3. Also provided are mutants of cortactin with decreased ability to interact with Arp2/3.</p> |
| 申请公布号 |
WO0218626(A8) |
申请公布日期 |
2002.07.04 |
| 申请号 |
WO2001US26834 |
申请日期 |
2001.08.29 |
| 申请人 |
THE AMERICAN NATIONAL RED CROSS;ZHAN, XI;URUNO, TAKEHITO |
发明人 |
ZHAN, XI;URUNO, TAKEHITO |
| 分类号 |
A01N65/00;A61K38/00;C12Q1/68;G01N33/574;G01N33/68;(IPC1-7):C12Q1/00;G01N33/53;A61K39/00;A01N61/00 |
主分类号 |
A01N65/00 |
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