发明名称 CDK4 INHIBITORS
摘要 <p>Compounds of the general formula (IA) or (IB) having cyclin-dependent kinase 4 inhibiting activity, or salts thereof: (IA) (IB) wherein X is S, O, or N-R5 (wherein R5 is hydrogen or alkyl); Y is N or CH; Z is N or C-R6 (wherein R6 is hydrogen, halogeno, or alkyl); R?1 and R2¿ are each hydrogen, alkyl, alkoxy, or the like; R3 is hydrogen, alkyl, or aryl; R4 is hydrogen or alkyl; and A is a group represented by the general formula (II) or the like: (II) (wherein R7 is hydrogen or alkyl; and R8 is alkyl, aryl, or a heterocyclic group).</p>
申请公布号 WO2002051849(P1) 申请公布日期 2002.07.04
申请号 JP2001011354 申请日期 2001.12.25
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