摘要 |
<p>Compounds of the general formula (IA) or (IB) having cyclin-dependent kinase 4 inhibiting activity, or salts thereof: (IA) (IB) wherein X is S, O, or N-R5 (wherein R5 is hydrogen or alkyl); Y is N or CH; Z is N or C-R6 (wherein R6 is hydrogen, halogeno, or alkyl); R?1 and R2¿ are each hydrogen, alkyl, alkoxy, or the like; R3 is hydrogen, alkyl, or aryl; R4 is hydrogen or alkyl; and A is a group represented by the general formula (II) or the like: (II) (wherein R7 is hydrogen or alkyl; and R8 is alkyl, aryl, or a heterocyclic group).</p> |