发明名称 Combination and method of treatment of cancer utilizing a COX-2 inhibitor and a 3-hydroxy-3-methylglutaryl-coenzyme-a (HMG-CoA) reductase inhibitor
摘要 The inventors propose a combination of an HMG-CoA reductase inhibitor (also referred to as "HMG-CoA inhibitor(s)"), and COX-2 inhibitor for the treatment of cancer especially prostate cancer and a method of treatment of cancer by that combination, especially prostate cancer. The inventors propose a combination of an HMG-CoA reductase inhibitor, COX-2 inhibitor, and glutathione pathway enhancing and detoxifying compound, particularly cystine, for the treatment of cancer especially prostate cancer and a method of treatment of cancer by that combination, especially prostate cancer. Based on the clinical results of retardation, but not cure of cancer, the combination has the characteristic of sufficiently interfering with replication and apparently restoring the immune system capacity to manage cancer.
申请公布号 US2002086894(A1) 申请公布日期 2002.07.04
申请号 US20010912703 申请日期 2001.07.25
申请人 KINDNESS GEORGE;SCHUMM BROOKE;GUILFORD F. TIMOTHY 发明人 KINDNESS GEORGE;SCHUMM BROOKE;GUILFORD F. TIMOTHY
分类号 A61K31/195;A61K31/198;A61K31/22;A61K31/225;A61K31/34;A61K31/35;A61K31/355;A61K31/365;A61K31/366;A61K31/385;A61K31/415;A61K33/04;A61K33/38;A61K45/06;(IPC1-7):A61K31/415 主分类号 A61K31/195
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