PROTEINIC ANTIGENS INDUCING ANTIBODIES NEUTRALISING HIV VIRUS

摘要

The invention concerns a proteinic antigen of formula P-E-S wherein: P represents a protein or a carrier peptide or a fragment derived therefrom; E represents a spacer arm of 2 to 25 amino acids, mainly consisting of glycine, proline or alanine; S represents a specific peptide sequence, said antigen being capable of inducing neutralising antibodies against HIV primary isolates and its use in an anti-HIV vaccine.