| 发明名称 |
MAP kinase integrin-binding domain |
| 摘要 |
Dislosed is the integrin-binding domain of MAP kinase. Interaction between MAP kinase and integrin via this domain activates MAP kinase and initiates cellular activity. Methods of modulating cellular activity by inhibiting direct MAP kinase-integrin binding are provided. These methods have particular use in inhibiting growth of cancer cells.
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| 申请公布号 |
WO02051993(A1) |
申请公布日期 |
2002.07.04 |
| 申请号 |
WO2001AU01672 |
申请日期 |
2001.12.21 |
| 申请人 |
THE UNIVERSITY OF NEWCASTLE RESEARCH ASSOCIATES LIMITED;AGREZ, MICHAEL, VALENTINE |
发明人 |
AGREZ, MICHAEL, VALENTINE |
| 分类号 |
A61K38/46;C12N9/12;(IPC1-7):C12N9/12;C12N15/12;A61K38/45;A61K48/00 |
主分类号 |
A61K38/46 |
| 代理机构 |
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