发明名称 VERFAHREN ZUR HERSTELLUNG VON ELASTISCHEM DEHYDRIERTEM IMPLANTATGEWEBE
摘要 A process for preparing pliable soft tissue specimen which are resistant to cracking and devoid of viable cells includes the steps of treating native soft tissue obtained from a donor by a gradually increasing gradient of aliphatic alcohol or other suitable water miscible polar organic solvent until the last alcohol (or other solvent) solution has at least 25% by volume of the organic liquid. Thereafter, the tissue specimen is treated with a solution containing glycerol or low molecular weight (<1000 D) polyethylene glycol, and polyethylene glycol of a molecular weight between approximately 6,000 to 15,000 D and heparin. Thereafter, the tissue specimen is briefly immersed in aqueous heparin solution, frozen and lyophilized. The tissue specimen is suitable for implantation as a homograft or xenograft, with or without rehydration.
申请公布号 DE69901612(D1) 申请公布日期 2002.07.04
申请号 DE1999601612 申请日期 1999.06.23
申请人 INTERNATIONAL HEART INSTITUTE OF MONTANA FOUNDATION, MISSOULA 发明人 DURAN, M.;CHEUNG, T.;PANG, C.
分类号 A61L27/36 主分类号 A61L27/36
代理机构 代理人
主权项
地址