| 发明名称 |
MUTANTEN VON HEPATITIS A VIRUS STAMM HM-175 ZUR VERWENDUNG ALS HEPATITIS A VIRUS IMPFSTOFFE |
| 摘要 |
<p>A live hepatitis A virus adapted to growth in MRC-5 cells, which HAV is preferably characterized by suitable attenuation for effective vaccine administration to humans and animals without inactivation, methods for adapting HAV to growth in MRC-5, vaccine compositions and method of vaccinating humans against HAV infection.</p> |
| 申请公布号 |
DE69330758(T2) |
申请公布日期 |
2002.07.04 |
| 申请号 |
DE1993630758T |
申请日期 |
1993.09.17 |
| 申请人 |
SMITHKLINE BEECHAM BIOLOGICALS S.A., RIXENSART;THE GOVERNMENT OF THE UNITED STATES OF AMERICA C/O AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES AND HIS SUCCESSORS, WASHINGTON |
发明人 |
FUNKHOUSER, ANN W.;EMERSON, SUZANNE U.;PURCELL, ROBERT H.;D'HONDT, ERIC |
| 分类号 |
C12N15/09;A61K35/76;A61K39/29;A61P31/12;C07K14/10;C12N7/00;C12N7/01;C12N7/08;C12N15/51;C12P21/02;C12R1/91;(IPC1-7):C12N15/51;C12N7/04 |
主分类号 |
C12N15/09 |
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